Thursday, February 28, 2008

Non motor or motor symptoms has great impact on PD

Non motor or motor symptoms has great impact on PD?

It is increasingly recognised that the non-motor effects of PD including depression and cognitive dysfunction can have a greater impact on patients' quality of life.

I agree. I can deal with the tremors and the dyskinesias; it is the neuropathies - the pain in my hands and feet - and the depression, that have a greater impact on me at this timelity of life than the movement symptoms


While that may be very true, I have more difficulty accepting not being able to write/print legibly and using the keyboard is becoming more and more difficult. At the same time, my vocal functions are decreasing as well.........voice is soft, words are sometimes slurred, occasionaly I have difficulty with swallowing and choking. I am very lucky NOT to have the pain so many of you have to deal with. Even tho, basically pain free, do not discount the loss of functions so many people take for grant


I think they are equal in impact. The difference in degree is of impact individually. I may not have pain and dystonia, but I do have major depression, dibilitating tremor, as well as profuse sweating...just to begin with. We ALL have some degree of lose of function. It is just differnet in each of us. And the difference isn lose of functon is not even the same; e.g. timing of lose from dx date

Source; PatientdLikeMe

Is it the cure the beginning or the end of life?





Post subject: Is it the cure the begining or the end of life?

Dear Doctor, Some patients leave their PD to the doctors and drugs for treatment as Parkinson's is a lifetime diseases. It is kill or cure.
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Dr. OkunJoined: 19 Jan 2007Posts: 251Location: University of Florida
Posted: Tue Feb 19, 2008 10:57 am Post subject:

Thank you for the post. I am a glass is half full person and in PD I am definitely that way. Most patients in point of fact do not die of their PD, they die of heart disease, cancer, stroke, vascular disease, etc. If your PD is well managed you may encounter difficult to treat symptoms but your quality of life and existence can usually be great. Keep your head up!_________________Michael S. Okun, M.D.










Water and Dehydration?

Water is the one of the most important components of cells in many vital organs (including the brain). Water plays a major role in maintaining the integrity of the blood-brain barrier. Thus, dehydration certainly causes brain cell dysfunction. However, it difficult to ascertain whether the degree of cell dysfunction, due to dehydration, is sufficient to lead to brain diseases such as Parkinson's Disease. Dr Chew, Neurologlist


Dr. OkunJoined: 19 Jan 2007Posts: 251Location: University of Florida
Posted: Fri Feb 29, 2008 1:10 pm Post subject:

Thank you for the comment. Dehydration has been linked to worsening symptoms, but is not linked to causing PD. I agree.


wheelersceJoined: 02 Mar 2007Posts: 357Location: MI
Posted: Thu Feb 28, 2008 7:54 am Post subject:

Teokimhoe, Of course, you are right that it's often "better to give than to receive." But I think we persons with Parkinson's have to understand that sometimes we simply have to focus on ourselves, and that's ok, too. We shouldn't feel guilty about it. And eventually, we will all be on the receiving end of help. There is beauty, too, in being a gracious receiver, allowing others the opportunity to give. It depends on where we are on this journey. Sue W



Thu Feb 28, 2008 11:09 am Post subject:

I agree with you both, but I have a hard time focusing on myself. Example: Yesterday I was able to get out of the house and visit with my Granddaddy, who is in the nursing home. He just found out he is getting a private room and so excited. So, here I go (not complaining), as excited as he, to get him things for his room that he wants. In the meantime, I am also looking for my friend some furniture for her childs room. I also had to buy groceries for my family but by the time I do all my running around and get to Wal-Mart, I give completely out, start shaking, feet dragging, my speech is slurred because I am exhausted. I decided to sit and rest and maybe I wil get my strength back to finish, but I didn't. I even had people come by and laugh at me. I finally had to call my dear husband to my rescue (once again). I was so frustrated with myself, but it happens so fast. I just can't figure out this balance of helping others but also taking care of myself. This disease is so unpredictable and real pain in the ___, but I am still blessed!!! Candy

Does anyone have feeling of fatique?

Does anyone else have this overwhelming feeling of fatique?

I often have fatique, but for the past 3-4 weeks around this time everyday, I get this overwhelming feeling of fatigue. I can barely hold my head up or talk. I guess my body is trying to tell me to rest. Does anyone else ever have that feeling?
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ahimsajackJoined: 25 Apr 2007Posts: 547
Posted: Tue Feb 26, 2008 4:02 pm Post subject:

Yes, either late morning or early afternoon I am force to take a nap for an hour. Being that I do not use any PD meds, I assume this is from the PD itself. Jack_________________We are what we think, with our thoughts we create our world.
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askoonzJoined: 07 Mar 2007Posts: 24
Posted: Tue Feb 26, 2008 4:15 pm Post subject:

Hi Candy, I also take no meds. In the afternoons around 3pm I also get very sleepy and just want to curl in a ball and sleep. If I take a nap then I will usually be up all night. Hope you survived the storms. We got another 3 or 4 inches of snow. I will be so happy for spring. We have just about had a record amount of snow.
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cfinlaysonJoined: 29 Jun 2007Posts: 44
Posted: Tue Feb 26, 2008 6:32 pm Post subject:

Thanks for your advice. I do take meds but still have this feeling aroudn the same time. I however, don't take a nap. I may sit and rest for a moment. I don't sleep well at night so I am afraid to nap during the day. I am not sure how much rain we did get, but our pond if finally beginning to fill up, which is a blessing for our cows. I will be glad with Spring gets here as well. I have all sorts of plans (in my head). Hopefully, we will manage to get a few of my projects done. Thanks and hope you both have a good night. Candy
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John ShJoined: 05 Mar 2007Posts: 136Location: Arroyo Grande, California
Posted: Tue Feb 26, 2008 6:33 pm Post subject:

I am the same as Candy and Jack, great fatigue, am also unmedicated. God, this PD is wearing me out. John S
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teokimhoeJoined: 03 Mar 2007Posts: 65Location: Malaysia
Posted: Wed Feb 27, 2008 10:00 am Post subject:

Fatigue Fatigue may refer to several things in neurological diseases:1.) A generalized lack of energy. 2.) A reduction in the force of individual muscle contractions; overlaps with weakness and atrophy.3.) A psychological state consistent with apathy, inertia, or lack of motivation such as occurs in depression. 4.) Daytime sleepiness caused by poor sleep quality or medication side effects. The management of fatigue is important because it is associated with poor quality of life. There are several targets for treatment. Firstly, sleep quality must be considered. Poor sleep hygiene, anxiety, inability to turn in bed, pain, or breathing difficulties could cause insomnia, leading to daytime sleepiness, irritability, and poor cognitive function. Treatment of these underlying causes may be beneficial. Secondly, poor respiratory function could lead to lack of oxygen for the brain and muscles. Non-invasive ventilation either at night or for periods of the day may be helpful. Thirdly, mood factors such as anxiety and depression can cause psychological feelings of fatigue or inertia, which may respond to drugs or counseling. Finally, a wakefulness-promoting agent such as Modafinil may be prescribed to combat fatigue. Source: NPF open forum_________________to help the PD patients aware the diseases and encourage to set up support groups to educate the patients and their immediate families
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Does everbody get worse?


Does everybody with Parkinsons Disease get worse, or do some people stay the same for years, or even improve ?
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ahimsajackJoined: 25 Apr 2007Posts: 545
Posted: Tue Feb 26, 2008 8:12 am Post subject:

Sorry to say, everyone gets worse, although at different rates. Jack_________________We are what we think, with our thoughts we create our world.
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johnball20@gmail.comJoined: 23 Feb 2008Posts: 3
Posted: Tue Feb 26, 2008 11:15 am Post subject: Does everyone get worse?

Well, I am not sure I want to agree with Jack, but I know that he is right in at least the sense that there is no cure for the disease itself. It will progress, and the number of affected brain cells will increase over time. Parkinson's is a degenerative disease, but the brain has shown a lot more neuroplasticity than was previously believed possible. I know that strenuous exercise has kept me thinking clearly and physically functional over the last 25+ years of living with this disease. I do think we have the ability to develop strategies that help us manage the disease better. I know my Parkinson's symptoms are more severe today than they were 25 years ago when I was diagnmosed, but I also know that iam in better physical shape today than I was then. I can still do all the things I want to get done during the day because I plan better, I work smarter, I get help when or if I need it, and I don't try to rush through things. We can get better, in spite of the disease getting worse. John
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ahimsajackJoined: 25 Apr 2007Posts: 545
Posted: Tue Feb 26, 2008 11:24 am Post subject:

John, thanks for the reminder. I agree with you totally. Even though PD progresses and cannot be stopped, the way we cope with it makes a huge difference. Our overall well being can actually improve in spite of the PD. As with you, I make daily use of exercise, prayer, meditation, and a positive outlook. Jack_________________We are what we think, with our thoughts we create our world.
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John ShJoined: 05 Mar 2007Posts: 136Location: Arroyo Grande, California
Posted: Tue Feb 26, 2008 12:41 pm Post subject: Providentia

I went back over to PDrecoverers@yahoogroups.com a couple of days ago, and got some responses. Providencia wrote a very interesting message that pretty well mirrors how I feel. She goes by "risingsuntouch." Check it out. John S
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John ShJoined: 05 Mar 2007Posts: 136Location: Arroyo Grande, California
Posted: Tue Feb 26, 2008 12:44 pm Post subject: Sorry

I goofed, you get the Yahoo email address. Sorry, John S
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John ShJoined: 05 Mar 2007Posts: 136Location: Arroyo Grande, California
Posted: Tue Feb 26, 2008 1:07 pm Post subject: I'll try once more

Try this....John S http://health.groups.yahoo.com/group/PDrecoverers/
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Archduke Ferdinand IIJoined: 12 Aug 2007Posts: 179
Posted: Tue Feb 26, 2008 2:34 pm Post subject:

I heard from somebody today who had classic Parkinson's Disease who doesn't have it any more, and is no longer taking any drugs for it. It hasn't been all in the wrong direction for everyone.
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John ShJoined: 05 Mar 2007Posts: 136Location: Arroyo Grande, California
Posted: Tue Feb 26, 2008 6:39 pm Post subject:

Is this the woman that you mentioned who was taking the dopavite?
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Archduke Ferdinand IIJoined: 12 Aug 2007Posts: 179
Posted: Tue Feb 26, 2008 6:56 pm Post subject:

Yes
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John ShJoined: 05 Mar 2007Posts: 136Location: Arroyo Grande, California
Posted: Tue Feb 26, 2008 7:08 pm Post subject:

Do you think you could interest her in telling us about her experiences with it? John S (the dopavite)
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teokimhoeJoined: 03 Mar 2007Posts: 65Location: Malaysia
Posted: Wed Feb 27, 2008 9:53 am Post subject:

Parkinson's is a life times disease and is "not going away" as different what other illness. It is a progression's disease. Medications and exercises could slowdown the disease but it is not cure or the end. There is still life after Parkinson's. With the vast improvement of the treatment people would not die from Parkinson's disease but die on other sickness. At least we could have a choice on medications. There are sideeffects on medications and it is indvidualised. The doctor finds difficulty to diagnose on early parkinson's patient as it is an age agining disease but also find at the younger age. Consistencies, persistence, determination, and perseverance on exercises and medications relieve your slow movement and stiffness muscles. It is not the treatment._________________to help the PD patients aware the diseases and encourage to set up support groups to educate the patients and their immediate families
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Joined: 03 Mar 2007Posts: 65Location: Malaysia
Posted: Wed Feb 27, 2008 10:07 am Post subject:

I refer Dr.Chew Nee Kong" Understanding Parkinson"s Disease " that the progression and survival in Parkinson's Disease as follows: The "honeymoon " period Following the improvement in the symptoms of PD with drug treatment, the early stage of PD patients generally do well during the first to seven years of treatment.- the "honeymoon " period. Despite taking small and infrequent doses of medications patients can usually keep "going strong" in their daily life. In the "honeymoon period" there are still relatively adequate "reserve " brain cells during the early stage of illness. The progression in PD Unfortunately, life is not that kind nor straightforward. The "honeymoon " period is rather short-lived. After five to seven years of treatment with levodopa, PD patients will have increasing slowness of movement and tremor. The physical disability us due to the progression of PD itself, appearance of levodopa -resistant symptoms or development of motor complication It is important to note that while levodopa relieves the symptoms and physical disability of sufferers of Parkinson's it does not by itself slow down the progression of illness. The improvement of survival of patients by levodopar is due to the reduced risk of getting bedridden. In fact PD patients have a higher chance of dying of other common diseases of the elderly, such as heart attack and cancer, than succumbing to PD itself. In short levodopa treatment improved the quality of life of sufferers of Parkinson's even though is not a cure for PD. Thus PD should never be regarded as an old people's disease for which nothing can be done._________________to help the PD patients aware the diseases and encourage to set up support groups to educate the patients and their immediate families
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Do you experience as an early PD patient?

Early parkinson's patient fully aware that the early stage of PD patient does not accept that he has symptoms of PD even have been diagnosed by doctors.. He treats it as an aging process as the result the patient end up with Parkinson's progression. Besides Parkinson's has symptoms with other related diseases and some doctors wrongly diagnosed as an age aging process. I am one of the sufferer's. It takes me four years to be treated as Parkinson's patient. I am fortunate that my PD is slow progression.as I do daily exercises far ahead for changes of my body.movement. The late Parkinson's treatment aggravates the sickness further and could not to be normal and enjoy good quality life. Therefore a good start to tackling health issues is to understand the diseases themselves. As an early PD patient I experience emotional disorders - anxiety,depression, apathy, uncertainties and stress.

Wednesday, February 27, 2008

Do you challenge the doctor?

Posted: Wed Feb 27, 2008 3:30 am Post subject: Do you challenge your doctor?

Doctors are human and human sometime make mistakes. Some doctors are good and some are bad. Let us share your experience "do you challange your doctor"? I have so far changed three neurologists. The first and second diagnosed me as age agiing and the third one diagnosed me as Parkinson's patient. It is not too late for me as I have learned to battle the disease besides I have a good neurologlist Dr. Chew for his excellent medications._________________to help the PD patients aware the diseases and encourage to set up support groups to educate the patients and their immediate families
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Rogerstar1Joined: 14 Mar 2007Posts: 229
Posted: Wed Feb 27, 2008 10:04 am Post subject:

Hi Teokimhoe: While I have not challenged my PD neurologist 'pill juggler' as new aches and pains have presented over the past twelve months in terms of distonia, arthritis, ulnar tunnel syndrome(?), carpel tunnel, a pinched nerve I discover I have outstrippped medical delivery systems and Drs who are not in communication. One set of x rays don't illuminate adequately for all physicians. They all need a unique set. Dr visits becsome a full time job and clear answers seem just as elusive. Alas...there is no cure after all. Best to you in Malaysia fr. Rogerstar.

Gambling and compulsions due to dopamine agonists

Post subject: Gambling and compulsions due to dopamine agonists

pokermid wrote:
I'm also a pathological gambler, a compulsion, brought on by the dopamine agonists prescribed to combat PD.I've brought this over from another Thread. Pokermid, gambling and other compulsions due to dopamine agonists has become quite an issue. How much did you gamble before you started dopamine agonists ? What sort of change in your gambling habits was there after you'd been taking dopamine agonists for a while ? What did you gamble on ? Did you also expand on what you gambled on because of the dopamine agonists ?
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pokermidJoined: 18 Jul 2007Posts: 199Location: CHELMSFORD, ENGLAND
Posted: Sun Feb 24, 2008 6:28 pm Post subject:

joe bob i liked a flutter as well as the next man in my world of construction workers. i would have a fiver on a tip in the pub, i would have a score on the national or the derby and i would play a few fruities down my local and maybe join in the lottery syndicate. i occasionally went with my wife to a race meeting with a coach load of friends, family or colleagues. lightweight stuff to what took over and nearly destroyed my life and all my loved ones. at first , i dismissed reports with the link with da's , but the snowball grew and i looked more closely at what i was taking , what it did , what it was meant to do, what it might do, and how my disease and body worked. even when i realised that da's were the culprit, i still couldnt stop. illogical? yes. i was in a bubble , and while i hads the money i would keep on until it had all gone. i break out now and then, when i can get my mitts on any wonga, but to a far lesser degree. i have only a rough guide to the total i have gambled and estimate a figure between £120,000-£140,000. you know what is happening but you cannot stop it. why did i continue, you ask? i can only say , i believe it to be the da's. and i will always be a pathological gambler whilst i am taking those class of drugs. i tried cutting my meds altogether several months ago, but that was a big mistake. and until they come up with an alternative , imy wife and i will try to be as vigilant as we can. she holds all the purse strings. i dont like it , but its the only way. pokermid_________________PEOPLE WITH PD USED TO BE CONCEITED, BUT NOW WE ARE ABSOLUTELY PERFECT!
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Archduke Ferdinand IIJoined: 12 Aug 2007Posts: 179
Posted: Mon Feb 25, 2008 5:35 am Post subject:

When I read the news reports concerning gambling and agonists, I wondered how much difference it makes. In your case it's taken you from average, no different from anyone else, to very serious. Can you substitute the dopamine agonists with something else ?
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teokimhoeJoined: 03 Mar 2007Posts: 61Location: Malaysia
Posted: Mon Feb 25, 2008 8:34 am Post subject:

I think that the mental side effects of Requip (Ropinirole) such as pathological gambling and hypersexuality have been over-publicized. Based own my own personal experience, Requip seldom causes mental side effects. Very often, Parkinson's patients are on more than one drug. Therefore, the mental side effects which are attributed to Requip could be actually caused by other medications. Dr Chew Nee Kong, Kuala Lumpur,Malaysia_________________to help the PD patients aware the diseases and encourage to set up support groups to educate the patients and their immediate families
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pokermidJoined: 18 Jul 2007Posts: 199Location: CHELMSFORD, ENGLAND
Posted: Tue Feb 26, 2008 1:05 am Post subject:

TO TELL YOU THE TRUTH. Oops big letters I no longer believe that its just the Agonists. whether its Dopamine from the Agonists or L-dopa from the Sinemet or Madopar, i dont really know! All i know is that i've had PD for 10-12 years and before i was prescribed Meds for this pox, I was just an average punter who enjoyed a game of cards for pennies, had a bet occassionally on the gee gees, bought a few lotto tickets and never ever contemplated gambling to the extent i have done. before , if i had a set, it was to try and win a few bob. what I am doing now is winning and just plowing everything back, regardless . its not logical. its not me. it doesnt make sense. i know what i am doing , but i cannot stop. stopping only becomes an option when you have nothing left. And when you have nothing, you then devise devious ways of obtaining money to fuel the need. Anyway at all. And as for Dr Chewbacca Who and what are you.? Do you work for a pharmiceutical Co? Do you have PD? Are you an expert on OCD? Are you a neurologist? What experiences are you talking about.? Why are you only talking of requip? I started on Pergolide (permax). I have seen too many similiar cases too dismiss these compulsions as anything other than the result from taking meds for my PD. These are very potent drugs and the human body is a very complex and intricate system , but also very vunerable. nobody truly knows what happens when the two combine. trial and error and forget about the casulties in between._________________PEOPLE WITH PD USED TO BE CONCEITED, BUT NOW WE ARE ABSOLUTELY PERFECT!
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teokimhoeJoined: 03 Mar 2007Posts: 61Location: Malaysia
Posted: Tue Feb 26, 2008 6:48 am Post subject:

Just to inform you that Dr. Chew is my Neurologlist who is a Movement Disorder specialist. He is a senior consultant Neurologist and a lecturer in the University of Malaysia. He is only the doctor in Malaysia who is in the field of Parkinson's diseases. He is the author of few books related Parkinson's disease. He is involved actively in Parkinson's association, Malaysia._________________to help the PD patients aware the diseases and encourage to set up support groups to educate the patients and their immediate families
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teokimhoeJoined: 03 Mar 2007Posts: 61Location: Malaysia
Posted: Tue Feb 26, 2008 8:23 am Post subject:

Requip is one of dopamine agonist that treats Parkinson's diseases. I am on Requip medication for the past of seven months. It is a wonder drug for some patients as it helps my movement mobility. Like other medications it has sideeffects. It is individualised. Discuss it with your doctor for advice_________________to help the PD patients aware the diseases and encourage to set up support groups to educate the patients and their immediate families,




pokermid wrote:
TO TELL YOU THE TRUTH. Oops big letters I no longer believe that its just the Agonists. whether its Dopamine from the Agonists or L-dopa from the Sinemet or Madopar, i dont really know!Pokermid, have you any experiences that would indicate that L-dopa also causes it ? It's widely reported that compulsive gambling is caused by dopamine agonists, but ultimately L-dopa and dopamine agonists have a dopaminergic effect. I can't see why L-dopa couldn't cause the same problems.
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pokermidJoined: 18 Jul 2007Posts: 199Location: CHELMSFORD, ENGLAND
Posted: Tue Feb 26, 2008 7:32 pm Post subject:

neither can I!!!! but i'm not really bothered anymore. Pd took over my life, but the meds destroyed it. what a paradox!!!!!_________________PEOPLE WITH PD USED TO BE CONCEITED, BUT NOW WE ARE ABSOLUTELY PERFECT!

Why Me?

: Why me?

No warning, no preparation The Doctor's word hung dead in the air you have "Parkinson's disease PD" . I had no idea about what he was talking about. And the doctor kept silent- that was the beginning of my journey that I have traveled for the past of three years........_________________to help the PD patients aware the diseases and encourage to set up support groups to educate the patients and their immediate families
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cfinlaysonJoined: 29 Jun 2007Posts: 43
Posted: Tue Feb 26, 2008 8:48 am Post subject:

I think that most of felt the same when we got the news. I did. I denied it for a long time and even thought that I was being punished for something I had done wrong in my life. But over time, through many trials and tribulations and many days of going to the Lord in prayer, I have been blessed in so many ways. My eyes have been opened as well as my heart to things that really matter on this earth. I have found out what needs and wants are. I have felt empathy and compassion as I never have before in my life. My heart aches for so many who have this disease as well as any heart ache in their life. I have found my strength in my faith and going to God in prayer and having a one on one relationship with him. I know others get their strength elsewhere. I do believe that having a positive attitude helps you get through so many things in life and prayer is very powerful. I am a Christian, and I am a sinner. We all sin everyday and we all get down from time to time. We are only human. I have asked many days why me Lord, but now I get up every morning and thank him for the blessings in my life. Don't get me wrong, Parkinson's Disease is not a blessing, but the way it has changed my life and with the help of God opening my eyes and softening my heart, has humbled me. I tell everyone in my life that if I had a choice to go through what my husband and I have been through over the last 3-4 years, I would do it again in heartbeat if I knew it would have brought me this close to Christ. I know not everyone feels the same way I do and not everyone has the same beliefs. But, when I say I am praying for you, I mean that in the most sincere and humble way. I will pray for you, not to offend you, not that I think you have something wrong with you, but because that is what I do, what I enjoy, what makes me feel good. If I know going to the Lord in prayer will help you deal with this disease or just to let you know that there is someone that cares for you and is concerned about your well being, then I will go to God in prayer as I do many times throughout my day. I hope that I haven't offended you, but I do care and I wish you the best. In Christian Love, Candy
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Archduke Ferdinand IIJoined: 12 Aug 2007Posts: 179
Posted: Tue Feb 26, 2008 2:19 pm Post subject:

cfinlayson wrote:
I denied it for a long time and even thought that I was being punished for something I had done wrong in my life. Parkinson's Disease is purely a biochemical problem. Nobody has caused it by the way they have behaved.Last edited by Archduke Ferdinand II on Tue Feb 26, 2008 2:48 pm; edited 1 time in total
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cfinlaysonJoined: 29 Jun 2007Posts: 43
Posted: Tue Feb 26, 2008 2:28 pm Post subject:

I never said that we have PD becasue of the way we behave. I was trying to make a statement and say that we are human and sometimes we question God. I don't use your quotes in any of my statements and I would rather you not use mine, unless you use the entire message. Thanks, Candy
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wheelersceJoined: 02 Mar 2007Posts: 350Location: MI
Posted: Tue Feb 26, 2008 2:40 pm Post subject:

I know that at first I was certain it was something I did, too, and I still wonder from time to time. Thanks for sharing, Candy. SW
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Archduke Ferdinand IIJoined: 12 Aug 2007Posts: 179
Posted: Tue Feb 26, 2008 2:59 pm Post subject:

cfinlayson wrote:
I never said that we have PD becasue of the way we behave. I was trying to make a statement and say that we are human and sometimes we question God. I don't use your quotes in any of my statements and I would rather you not use mine, unless you use the entire message. Thanks, CandyI quoted only one sentence out of what you had written to show what I was referring to. Although you don't, some people do - very wrongly - almost feel guilty about having Parkinson's Disease.
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AhimsajackJoined: 25 Apr 2007Posts: 542
Posted: Tue Feb 26, 2008 4:25 pm Post subject:

Just to throw my lousy two cents into this thread. As a scientist my brain agrees with Joe or Bob, PD has nothing to do with our behaviour, or does it? There is some hypothoses that statistically correlate PD with one's profession, and location(exposure). That was my scientific answer. Now for a spiritual answer. I am not a member of any religion but do kind of follow Hinduism and Buddhism, each of which has the concept of karma, you reap what you sow. I am not saying that I totally believe this, nor am I implying any of you deserve PD. No one does. I am only putting another idea on the table. Jack_________________We are what we think, with our thoughts we create our world.
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Tuesday, February 26, 2008

Can Exercise do for Parkinson's Patients what medicine can't

Post subject: Can exercise do for parkinson's patients what medicine can't

Besides exercises medication are important for PD patients. Medications help you to relieve your body movement and mobility as to help you during exercises. Both are related. Consistencies, persistences, dsciplines towards exercises besides medication are the key for you to combat the diseases. I spend nearly three years in the fitness centre three hours daily in gym exercises classes i.e Yoga, body combat, spinning, body pump except Sunday. I finally combat the disease. I do not look like Parkinson's Patient as told by my neurologlist, fitness members and instructors. Besides I engage two personnel trainers to align my body posture and do strectching my stiffness muscles. I do Box and Kick exercises and cardio as well as weights lifting two times a week and last an hour to train my endurance and flexibility. Is it hard work? Can you do? Is it mad that I am a Parkinson's patient? Do you believe?_________________to help the PD patients aware the diseases and encourage to set up support groups to educate the patients and their immediate families
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wheelersceJoined: 02 Mar 2007Posts: 348Location: MI
Posted: Tue Feb 26, 2008 5:33 am Post subject:

Teokimhoe, You really are a fighter! I'm afraid most of us couldn't manage your routine. The studies seem to agree with you, that not only exercise, but hard exercise, can help whip PD. Still, I figure moderate exercise is better than none, so I do my daily walk and modest workout. I wouldn't say you're mad, but you are perhaps eccentric--and that's just fine! Thanks for sharing. Sue W.



Dear Mr Teo

Both medications and regular physical exercise are helpful - they complement each other in the treatment of PD. Exercise helps to maintain body fitness. For the purpose of carrying out regular exercise, the PD patient should be taking adequate dose of medications (obviously). A common observation in Malaysia is that there are many PD patients who do not carry out physical exercise simply because they are under-medicated.

In our country, the treatment of PD is rather conservative - the total daily dose of medications is relatively low compared with other countries. This is a pity because without adequate dose of medications, many of our PD patients are deprived of activities such as physical exercise, driving, etc. Dr Chew Nee Kong, Kuala Lumpur.

Discussion: Boxing-punching exercises

What's Being Discussed Here? boxing, GYM, mobility, yoga, Exercise, NOW, Yoga, Off balance

Anybody else hitting the heavy bag or boxing for PD therapy?I saw an article about how it improved PD symtems.My doctor recommended it and said a gym in Indy is giving free lessons to PD patients.All I know it really helps workout your frustrations.I've added it to my workout and I feel pretty good afterwardsBonecrusher

It is a good exercise for Parkinson Patient.I am taking this Box and Kick Exercises (Thai Boxing) for two and half years in my fitness centre besides body combat. I engage a trainer to guide me two times a week and each training last for a hour. It is advisable to engage a trainer as PD patients would find difficulty to do box and kick exercises as it involves your body balance and mobility. You need endurance and flexibility.After spending three hours in gym fitness centre daily except sunday. I attend class exercises, yoga, body combat, pump and spinning I do not look like Parkinson patient as I am now normal as told by my doctor and friends in the fitness centreI am a PD fighter and hero. I battle with Parkinson for two and half years. The credits are my consistencies, preservation,endurance and discipline towards exercises and medications. I wish to thank Dr.Chew Nee Kong, my neurologlist for his excellent medication.

TEOKIMHOE I live about 1 1/2 hours SE of Indy and can't see paying for the gas to get there so I just punch the bag I have in the basement along with my regular workout.I agree that exercise and staying active is great therapy for PD.It really helps me with my stiffness along with my mental well being.Sometimes it's hard to find the time or keep myself motivated to stay on top of it,but I always feel better afterwards


Source: PatientsLikeMe

Can Exercise do for Parkinson's Patients what medicine can't

Can exercise do for Parkinson's patients what medicine can't?http://www.king5.com/health/stories/NW_020408HEK_exercise_parkinsons_SW.8cf26b71.html#
06:10 PM PST on Monday, February 4, 2008JEAN ENERSEN / KING 5 News
Sixty-one-year-old John Kendell isn't an athlete, but for the last two months, he's been hitting the gym.
At first, his Parkinson's disease made it tough.
"I was stiff and my hand didn't move along my side," he said.
But now, he says, "At this slower speed we're going now, I can stand and I can think about moving my hand."
Alan Sidlowski has trouble with simple movements.
"I had very limited mobility in my hand and my leg," he said.
But after seven months in the gym he's made improvements.
These men are part of a study aimed at finding out if exercise can do what medication often can't for patients with Parkinson's.
"Medications have been somewhat disappointing to prevent disability related to walking and balance," said Dr. Lisa Shulman, Associate Professor of Neurology at the University of Maryland.
Researchers say strength exercises, aerobic activity or gait practice may actually be able to retrain the brain.
"The potential for exercise to cause some rewiring and remodeling would be effective in either case," said Shulman.
Physical and emotional improvements for each of 70 patients will be monitored for three months.
"Frankly, if it showed improvement in those areas alone, that would be a big advance," said Shulman.
Official results are two years away, but so far the results are encouraging. Their progress is a good sign.
It's estimated about 1.5 million Americans have Parkinson's disease. Only one in 10 people with the disease is diagnosed before age 50

Besides exercises medications are important for PD patients as it helps your body movement and flexibility as well as mobility. Consistenance, persistence, endurance and medication are the key for you to combat the disease.

TEOKIMHOE

Source: PatientsLikeMe

Exercise for Parkinson

Exercise for Parkinson's
Friday, February 15, 2008 6:22 PM
When a person is diagnosed with a neurological condition like Parkinson's -- medications do not always help.
By Dr. Jay Adlersberg
http://abclocal.go.com/wabc/story?section=news/health&id=5960828 Watch Video also.
But now doctors say exercise may be the answer. Seven's on Call Dr. Jay Adlersberg has more.
Most medical studies look at the effects drugs have on various diseases. But doctors in Maryland want to see if good old sweat and hard work can make a difference for patients with Parkinson's.
John Kendell, 61-year-old, isn't an athlete. But for the last two months, he's been hitting the gym regularly.
At first, his Parkinson's made it tough.
"I was stiff and my hand didn't move along my side," said John Kendell.
But now...
"At this slower speed we're going now, I can stand and I can think about moving my hand," said John Kendall.
Alan Sidlowski has trouble with simple movements.
"I had very limited mobility in my hand and my leg," said Alan Sidlowski.
But seven months in the gym and...
"I've improved tremendously," said Alan Sidlowski.
These men are part of a study aimed at finding out if exercise can do what medication often can't for patients with neurological conditions like Parkinson's.
"Medications have been somewhat disappointing to prevent disability related to walking and balance," said M.D. Lisa Shulman, associate professor of neurology at University of Maryland School of Medicine.
Researchers say strength exercises, aerobic activity or gait practice may actually be able to retrain the brain.
"The potential for exercise to cause some rewiring and remodeling would be effective in either case," said Lisa Shulman, M.D.
Physical and emotional improvements for each of 70 patients will be monitored for three months.
"Frankly, if it showed improvement in those areas alone, that would be a big advance," said M.D. Shulman.
Official results are two years away, but so far...
"I'm a lot better now than I was. But who knows what's going to be," said Alan Sidlowski.
Their progress is a good sign.
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Monday, February 25, 2008

Diagnose

Date: Sat, 20 Oct 2007 02:01:22 -0700From: teokimhoe@yahoo.comSubject: Phlegm,Saliva, Cough and InsomniaTo: nkchew33@hotmail.com
Dear Dr. Chew,

I am glad that you are my respected doctor.

You are working hard for the awareness of Parkinson's patients..

In view of the above articles I am recently diagnoised that I have reflux acid. It causes saliva drooling from my mouth and excessive phlegm deep in my throat.

I have poor cough occassionlly when I lie down at bed. My phlegm is thin as a glue. I do not have COPD (Chronic obstructive pulmonary disease} as told by my Pulmonary specialist.

As what you have mentioned the Parkinson's medication known as agonists, such as Requip can cause bloating,saliva and phlegm deep in the throat that irritated with cough when one rests at bed.

I could not sleep at night and taking "Ativan "and it wear off in 3- 4 hours thus no relief from my early morning awakening.

I have consulted Lung Specialist for the treatment and am taking two doses of Prevacid 30 mg before food daily. As for my insomnia 2 doses of Ativan taking before bed time.

In this connection should I cutdown the taking of Requip from 12 mg to 8 mg and substitute with one extra of Sinemet from two doses to three doses daily? Sinemet is the wonder drug.
However I am worry does the changes affecting my physically agility at the Gym?

In this connection kindly advise me on how to get away or substitute the taking "Ativan" for insomnia as it has sideeffect if I regular use over time and increase significant risks in the elderly like me. It could develop over-sedation, confusion and balance impairment increasing the risk of falls.
Kindly advise me soonest;
TEOKIMHOE

Bad Dream

Dear Dr. Chew,I have bad dream and shouting in bed in the middle of night and I am awak at the time and is one only incident happend so far. after taking medications as follows: 8 mg Requip and 3 doses Sinemet 25/100 daily.I am changing one dose of Sinemet for evening to 2 mg of Requip instead and is getting fine now.Best regardsTEOKIMHOE

Medication

Dear Mr Teo
The mopst important lesson that I have learnt from PD patients is that each and everyone of them is different from each other. Every PD patient progresses at different rates, and develops different combinations of complications.
Thus, we should always try to remember that the management of each PD patients must be individualized.
As each patient has different response to medications, I usually need at least two to four weeks before I am confident of the optimal dosage of daily medications.
Dr Chew Nee Kong, Kuala Lumpur, Malaysia

Reflux Acid

Dear Dr. Chew,

I am glad that you are my respected doctor.

You are working hard for the awareness of Parkinson's patients..

In view of the above articles I am recently diagnoised that I have reflux acid. It causes saliva drooling from my mouth and excessive phlegm deep in my throat.

I have poor cough occassionlly when I lie down at bed. My phlegm is thin as a glue. I do not have COPD (Chronic obstructive pulmonary disease} as told by my Pulmonary specialist.

As what you have mentioned the Parkinson's medication known as agonists, such as Requip can cause bloating,saliva and phlegm deep in the throat that irritated with cough when one rests at bed.

I could not sleep at night and taking "Ativan "and it wear off in 3- 4 hours thus no relief from my early morning awakening.

I have consulted Lung Specialist for the treatment and am taking two doses of Prevacid 30 mg before food daily. As for my insomnia 2 doses of Ativan taking before bed time.

In this connection should I cutdown the taking of Requip from 12 mg to 8 mg and substitute with one extra of Sinemet from two doses to three doses daily?

Sinemet is the wonder drug. and is or one of the dopaminw agonist if dosed late in the day are probably most beneficial due to the long duration of action of these compound preventing resumption of sleep in the middle of the night.
However I am worry does the changes affecting my physically agility at the Gym?

In this connection kindly advise me on how to get away or substitute the taking "Ativan" for insomnia as it has sideeffect for regular users and increase significant risks in the elderly like me. It could develop over-sedation, confusion and balance impairment increasing the risk of falls.
Kindly advise me soonest;
TEOKIMHOE

Forum: Double Vision with PD

My brother is a PD patient.He has double vision.He is forgetful the exit where the entrance he comes.He finds diffiulties to drive car, to see object or faces , to read newspaper or TV.He sees object/things differently or varieties with the times changes i.e day and night.He could not read with his muti purposes glass as he has long and short eyes sighted.He prefers to use mircosope than glass to read or sees things at close distance to relief his double vision.He has impaired vision as he finds not comfortable with colours .Yet he is told by eye specialist that there is nothing wrong with his eyes.Are they related with PD?

If you go up to the top of this page where it says search topic and type in double vision back in November there was quite a discussion and quite a bit of info from everyone regarding double and blurred vision check it out teokimhoe
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Source: PatientsLikeMe

Dry Mouth: Benzhexol

How to deal with dry mouth? Medication?Sticky,thick saliva causes PD patient with dry mouth and difficulty to talk as your tongue is rough. They have cracked lip sat the corners of the mouth. This is the sideeffect of Benzhexol. This medication helps the PD patients from drooling the saliva from the mouth as the result the saliva become thick and sticky.

teokimhoe,What is Benzhexol? I have at times, had exactly as you describe with dry mouth but I don't have any medication with that name.When dry mouth occurs I love to put ice chips in my mouth. My kids would say welcome to dry mouth because I do not talk as much!!

I get dry mouth from Benedryl and from tea, and listerene. Quite a few, if not all of the PD meds list dry mouth as a side effect. As I posted in another thread, my dentist and my hygeniest daughter say this can cause gum and teeth problems. The thing to watch for os red swollen gums, and crowns falling out.

Source: PatientsLikeMe

REQUIP (Ropinirole) and Compulsive Behaviours

Requip is dopamine agonists. It is different with Levodopa. Both are the most effective medications for the treatment of PD, and are considered the firsr line of treatment. It depends on dividual whether they have compulsive behaviour.I am taking 12 mg Requip and one Sinemet 20/100 mg daily. It improving my movement mobilities. Thank to my doctor Chew Nee Kong


Requip is one of dopamine agonist that treats Parkinson's diseases. I am on Requip medication for the past of seven months. It is a wonder drug for some patients as it helps my movement mobilities. Like other medications it has sideeffects if you continue as it depends individual. Discuss with your doctor for advice.

I have been taking 24 mg of requip for about 1&1/2 years now and have developed compusive behaviors over the last year that my Neuro feels is severe enough to cut back the requip over the next month to a minimal dose and then stop altogether. He has been researching his problem and recognised it in me when I approached him for help. Requip works wonders in some patients but the side afects are too severe for me. ..............Just an update... it has been 2 weeks now since I have stopped taking requip and do feel more in control. I had to increase the sinemet to compensate

Requip is Like all the other PD meds, it helps some with no side effects, it helps others but has side effects, and finally it gives some only the side effects. One will experience this with all the meds, but there is hope. Keep an open dialog with your doctor and us. Your doctor is there to listen to you and change your meds or adjust your dose to fit your needs.




....requip can make you do some really strange things. For instance with me it wasn't gambling it was puzzles. In the past three months I have completed no less than seventeen 1000 piece puzzles, mounted them and put them on the wall. I have gotten so many that I sign them and if you come visit me you pick out a puzzle and I send it home with you. I only like a certain kind and the harder the better. I always keep two back so I don't run out and I can spend HOURS just working on these. I just finished a 500 piece one in 12 hours. Now am I sick or what. I'm trying to channel my compulsivness somewhere else and so now it's PLM. I'm hoping to take it one step further and focus on eating right and less. I'm thinking there could be a positive side to this
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Forum: Physical Trainer?

Toekimhoeyour post comes at a crucial time for me. I do not present with tremors. My PD presents with movement disorder. I shuffle lately a lot when I walk, my legs are soo very heavy. I am in pain, my entire body hurts daily 24/7 as if it has been beaten up. My newest issue is my arms have a deep ache along with my hands feeling swollen and tight but there is no visible swelling. Last night my psycologist and I made a pact that I would start back with the trainer and do stretching exercise this week with the balance ball. I am going to make an effort to exercise inspite of the pain. It is painful to lift my legs to get dressed! So I am not quite sure how exercising will go, but hey I am going to give it a shot. So far Mirapex is innafective as far as I am concerned...I guess I am at the height of frustration, but accept that I need to do more than just get up and go to work everyday and maintain this 3,700 sq foot home...obviously that is not enough...It is getting harder and harder to move. I am glad that you are doing so very well and have found so much success in your treatment plan. The fact that you can do any type of exercises is simply amazing, but then again PD hits all of us differently. Best of luck to you
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I am glad that you have a trainer to do stretching of your muscle stiffness and rigidity. He would help you and it takes times that you would be comfortable. Parkinson's disease would not going away like other diseases . Lord bless

Your trainer who understand your muscle stiffness and help you to stretching and take times to get away to be normal. Pray Lord that He give your strength and wisdom for your movement exercises. I have two trainers and my consistance and Preservation that I battle the diseases with success.Believe and trust the trainer who experience movement exercises help you to design a training program. Lord bless

Source: PatientsLikeMe

Can you do it?

Consistence and preservation are important for Parkinson's patients to combatthe diseases. You have to engage the trainer to strectching your muscle stiffness and movement mobilities.It takes me two years to slowdown my PD progression. ' Can you do it?

What's about you?

In order to combat the Parkinson's disease movement exercises are important and medications. I have two muscle trainers who do stretching my stiffness part of my muscles and movement mobilities. They spend two years for my movement mobilities and strecthing exercises. I am glad that my doctor told me I do not look like Parkinson's Patient. I could do whatever exercises. All my fitness members surprise my achivement as I have fighting spirits to combat the diseases. What's about you?

Is PD a progressive muscles movement disorder?

PD is a muscles movement disorders.
It is a chronic neurogical illness i.e. not going away" PD patients are different from what we define themself as "patient" i.e only during acute, self-limited illness or injury that temporarily impact their lives as an inconvenience or comfort.
The major functions of muscles are to produce movements of the body, to maintain the position of the body against the force of gravity,to produce movements of structures inside the body, and to alter pressures or tensions of structures in the body. The symptoms of muscles disorders are as follows: 1. Bradykinesia i.e. slowness of movement 2. Resting tremor i.e shaking,either one or both side 3. Rigidity i.e. marked stiffness 4.Decreased arm wing on one or both side 5. Problems with walking and balance i.e. freezing being unable to initiate a step forward 6. Small, cramped handwriting 7. Masked face ie. reduced facial expression 8. Low voice i.e not clear Therefore PD patients have to choose an exercises that gets their muscles moving i.e stretching, in order to overcome the muscles stiffness, rigidity and slow movement. A physiotherapy or doctor my be consulted as how to start on an exercise routine.

Sunday, February 24, 2008

Sideeffect of Sinemet CR

Too much Sinemet CR may cause muscle twitches, inability to open the eyes [including sleepiness], or other symptoms of levodopa overdosage. After taking Sinemet CR, if you feel that overdose is suspected, then contact with your doctor immediately."and from InhousePhamacy.com

Warnings and Precautions
When patients are receiving levodopa monotherapy, levodopa must be discontinued at least 8 hours before therapy with Sinemet CR is started (at least 12 hours if slow-release plain levodopa has been administered).
Dyskinesias may occur in patients previously treated with levodopa alone because carbidopa permits more levodopa to reach the brain and, thus, more dopamine to be formed. The occurrence of dyskinesias may require dosage reduction.
As with levodopa, Sinemet CR may cause involuntary movements and mental disturbances. These reactions are thought to be due to increased brain dopamine following administration of levodopa. Dosage reduction may be required. All patients should be observed carefully for the development of depression with concomitant suicidal tendencies. Patients with past or current psychoses should be treated with caution.
Sinemet CR should be administered cautiously to patients with severe cardiovascular or pulmonary disease, bronchial asthma, renal, hepatic or endocrine disease, or a history of peptic ulcer disease or of convulsions.
Care should be exercised in administering Sinemet CR to patients with a history of recent myocardial infarction who have residual atrial, nodal, or ventricular arrhythmia. In such patients, cardiac function should be monitored with particular care during the period of initial dosage administration and titration.
Patients with chronic wide angle glaucoma may be treated cautiously with Sinemet CR, provided the intraocular pressure is well controlled and the patient monitored carefully for changes in intraocular pressure during therapy.
A symptom complex resembling the neuroleptic malignant syndrome including muscular rigidity, elevated body temperature, mental changes, and increased serum creatine phosphokinase has been reported when antiparkinsonian agents were withdrawn abruptly. Therefore, patients should be observed carefully when the dosage of carbidopa-levodopa combinations is reduced abruptly or discontinued, especially if the patient is receiving neuroleptics.
Sinemet CR is not recommended for the treatment of therapy-induced extrapyramidal reactions.
Periodic evaluations of hepatic, haematopoietic, cardiovascular and renal function are recommended during extended therapy.

Source PatientsLikeMe

The Key to fight the PD

The key to fight the Parkinson's disease are as follow: Understand the symptoms of PD as knowledge is a power. Physical exercises to stretching the slowness of movement and relieve the stiffness of your muscleMedication is to help you to slowdown the diseases. Prayer is to comfort your mental uncertainies.Nutrient are important for Parkinson's patients as it help them to batttle with Parkinson's disease. Blood test are neccessary to exam the level of your vitamin and mineral.

Antioxidant is helpful for PD patient.As it helps patient who is malnutrition

Nutrients and Parkinson's

As Parkinson's disease (Lifetime partner) is a not going away disease we need nutrient(weapon) to battle the diseases from it's progression and slowdown the diseases. Besides exercises to strenthen your muscle stiffness and rigidity and mobilities nutrients are important for us to arm ourself to fight the PD. As Parkinson's have motor and non motor symptoms, Nutrients help patient stay healthy and keep fitHowever the more you exercise you need more nutrients to protect yourself from oxidative stress whether you are athletics or notI understand most PD patients have deficiencies or decreasing of antioxidants, frolic acid and Vitamin B 12 or 6 and these deficiencies occur in old adult too

Potassium

I'd like to share the following Information about Potassium: potassium, a mineral element and an importantn constituent of the human bodyIt is the main base ion of intracellular fluid. together with sodium it helps to maintain the electrical potential of nervous system and is thus essential for the functioning of nervous and muscle.Patient with deficiency may lead to general muscle paralysis.

Exelone Patch

Battle Parkinson’s Blog

12 Nov, 2007 Treating Parkinson's
The FDA has announced approval of the Exelon Patch (rivastigmine transdermal system) as an alternative to oral administration of Exelon to patients with mild to moderate Parkinson’s Disease Dementia (PDD).
What is Exelon?
Exelon prevents the breakdown of acetylcholine in the brain, a chemical that is important to the process of thinking, memory and reasoning. People with dementia usually have a diminished level of acetylcholine. The changes in Parkinson’s dementia involve the neuronal pathways in the brain. Exelon therapy enhances these neuronal functions by increasing the concentration of acetylcholine thereby moderating the effects of dementia. But, Exelon’s effect may lesson when the disease progresses as fewer neurons remain functionally intact.
How well does it work?
The effectiveness of Exelon was proven by a clinical test using the Alzheimer’s Disease Cooperative Study - Clinician’s Global Impression of Change (ADCS-CCIC).
541 patients were randomly chosen and treated with either Exelon, or a placebo. In two months there was little if any change in the patients, but after six months 56% of the untreated patients worsened and after 12 months 81% had worsened. Only 2% of the Exelon treated patients showed minimal worsening.
Dosage and Administration
The starting dose of Exelon is 3 mg a day in two 1.5 mg doses. The dosage may be increased to 3 mg, 4.5 mg and 6 mg based on tolerability with a minimum of four weeks at each dose.
Exelon can be taken orally, capsules or liquid, and now, through a transdermal patch. Exelon comes as a liquid in a 2mg/mL, clear, yellow solution in a 4 oz bottle with an oral dosing syringe, and as a 1.5 mg yellow capsule, a 3 mg orange capsule, a 4.5 mg red capsule, and a 6 mg orange and red capsule. Exelon patches are available in a 4.6 mg/24 hours and 9.5 mg/24 hours versions.
More details about the Exelon patch can be found here.
What other information should I know?
It is important to use Exelon regularly to receive the most benefit.
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and take the scheduled dose only. Do not take extra medicine to make up for the missed dose.
If you stop taking our medication for any reason you may have to restart it at the lower dosage.
Take Exelon with food. Swallow the capsule with a full glass of water. Stir the liquid form into a glass of water, fruit juice or soda. It can also be swallowed directly from the provided oral syringe.
If you need to have any type of surgery tell the surgeon you are taking Exelon.
Exelon Side Effects
Exelon use can cause significant stomach-related side effects including nausea, vomiting, loss of appetite and weight loss. Treatment should be reinstated at the lowest daily dose if an interruption in therapy occurs longer than several days.
Summary
Exelon is the first drug approved by the FDA specifically for the effective treatment of mild to moderate Parkinson’s disease dementia. The Exelon Patch is a significant development in the administration of the drug by improving tolerability, and by providing a continuous delivery of medication through the skin over a 24 hour per
13 Comments so far »
big daddy said
am December 11 2007 @ 7:42 pm
Hi!
The patch is a swell idea. Two most common effects of PD is fatigue and tremors. In moderate cases of PD, these symptoms might be slight and a transdermal patch will ensure that patients will receive the required dose regularly without being reminded or having to go fetch and handle a glass of water.
Thanks for the info.
Sonny said
am December 11 2007 @ 9:28 pm
Exelon will be a great help if your following the instruction mentioned. Patients must take a note and paste it somewhere where he could easily find it.I think the place is the ref, you can always see the instructions there.
low voltage license said

medicine to be optimized

Dear Dr, Chew,

Just to inforn you that I stop taking one dosage of sinemet 25/100 daily. Instead I replace 1/2 dosage of sinemet cr i.e 1 1/2 dosage of sinemet cr daily

I try to optimize my medication.

Best regards


Yours faithfully

Kim Hoe

Sideeffect of Amantadine

Dear Dr.Chew,

I have reddish mottling on my skin i.e some part of my body and legs which I believe to be sideeffect of Amantadine.

I have stopped taking.

Kindly advise me.soonest

Best regards

TEO KIM HOO

Water and dehydration

Dear Mr Teo

Water is the one of the most important components of cells in many vital organs (including the brain). Water plays a major role in maintaining the integrity of the blood-brain barrier. Thus, dehydration certainly causes brain cell dysfunction. However, it difficult to ascertain whether the degree of cell dysfunction, due to dehydration, is sufficient to lead to brain diseases such as Parkinson's Disease. Dr Chew
Date: Mon, 4 Feb 2008 16:56:53 -0800From: teokimhoe@yahoo.comSubject: commentTo: nkchew33@hotmail.com

Dear Dr. Chew,

Kindly comment the following articles.

Thanks

TEO KIM HOO

Teo, I don't know if you read all of the posts / replies so I am copying part of a reply that I sent to a post about Dehydration and PD. I would like your opinion as to what your thoughts are about the quoted material. Thanks, Janice (auntique) The book , "YOU'RE NOT SICK, YOU'RE THIRSTY" 'Water for Health, for Healing, for Life' by F. Batmanghelidj (Warner Books) will really open your eyes up to some things that we may be taking meds for that drinking more water would 'fix.' To quote a parargraph that I found extremely interesting: (please note I am not suggesting anything by quoting this to you, only sharing what the book says)'DEHYDRATION CAN CAUSE A BREACH IN THE BLOOD-BRAIN BARRIER. ANY SUCH BREACH COMPROMISES THE INTEGRITY OF NORMAL BRAIN FUNCTIONS. I (the author) AM OF THE STRONG OPINION THAT DEHYDRATION THAT COMPROMISES THE PROTECTIVE SHIELD OF THE BLOOD-BRAIN BARRIER IS THE PRIMARY CAUSE OF MOST OF THE DISEASES OF THE CENTRAL NERVOUS SYSTEM. WHEN THE BARRIER BECOMES COMPROMISED, THE SOLID WASTE OF SUCH MICROSCOPIC BLEEDINGS IS CONVERTED INTO PLAQUES THAT ARE THE HALLMARKS OF MOST NEUROLOGICAL DISORDERS, SUCH AS MULTIPLE SCLEROSIS, PARKINSON'S DISEASE, AND ALZHEIMER'S DISEASE. I (the author) THINK THE SAME PROCESS TAKES PLACE IN MIGRAINE HEADACHES

Teo, I agree 100%. Water is very very important. It does many things for us, keeps our blood thin and flowing, maintains our cells, helps all our vital organs, helps keep our sinuses and other muccuos membranes lubricated, and helps greatly with our bowels, and skin tone.

Source PatientsLikeMe

Symmetrel (Amantadine)

Symmetrel
Amantadine is an antiviral drug used to reduce on/off fluctuations and involuntary movements (dyskinesias) in Parkinson's disease.

It was approved by the Food and Drug Administration in 1976 for the treatment of Influenzavirus A in adults. In 1969 the drug was also discovered by accident to help reduce symptoms of Parkinson's disease and drug-induced extrapyramidal syndromes. It is a derivative of adamantane, like rimantadine, a similar drug.
As an antiparkinsonic it can be used as monotherapy; or together with L-DOPA to treat L-DOPA-related motor fluctuations (i.e., shortening of L-DOPA duration of clinical effect, probably related to progressive neuronal loss) and L-DOPA-related dyskinesias (choreiform movements associated with long-term L-DOPA use, probably related to chronic pulsatile stimulation of dopamine receptor

SIDE EFFECTS: This medication may cause stomach upset, nausea, drowsiness, constipation, headache, dizziness, anxiety, or purplish-red blotchy spots on the skin during the first few days as your body adjusts to the medication. If these symptoms persist or become severe, inform your doctor promptly. Notify your doctor if you develop: slurred speech, shortness of breath, swelling of the ankles/feet, unusual fatigue, vision disturbances, difficulty urinating, skin rash, mental/mood changes (sometimes severe, including rare thoughts of suicide), muscle stiffness, uncontrolled muscle movements, unusual sweating, fast heartbeat, unexplained fever. If you notice s).


Source: PatientsLikeMe

Carbidopa and Levodopa

madopar 100/25, Sinemet 10/100, Carbidopa levodopa CR, Half Sinemet CR, Sinemet CR, Sinemet Plus, Parcopa, Sinemet-25/100, Sinemet 50-200 CR Tabs, 88/Mylan, oval, purple, APO-LEVOCARB, generic, lodosyn, Sinemet, Stalevo
Levodopa is a dopamine precursor used to treat the movement disorder symptoms of Parkinson's disease. Carbidopa is often included with levodopa-containing drugs (such as Sinemet) in order to boost its efficacy by slowing down the metabolism of dopamine. Read more...
More about Carbidopa/Levodopa
You can read more at US National Library of Medicine Medline Plus: http://www.nlm.nih.gov/medlineplus/druginfo/medmaster/a601068.html

What side effects can this medication cause? Return to top
Levodopa and carbidopa may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:
dizziness
nausea
vomiting
loss of appetite
diarrhea
dry mouth
constipation
change in sense of taste
forgetfulness or confusion
nervousness
nightmares
difficulty falling asleep or staying asleep
headaches
weakness
increased sweating
drowsiness
Some side effects can be serious. If you experience any of the following symptoms, call your doctor immediately:
unusual or uncontrolled movements of the mouth, tongue, face, head, neck, arms, and legs
fast, irregular, or pounding heartbeat
depression
thoughts of death or killing oneself
hallucinating (seeing things or hearing voices that do not exist)
swelling of the face, throat, tongue, lips, eyes, hands, feet, ankles, or lower legs
hoarseness
difficulty swallowing or breathing
hives
black and tarry stools
red blood in stools
bloody vomit
vomiting material that looks like coffee grounds

Source: PatientsLikeMe

Motilium

A Canadian brand name for Domperidone used together with metoclopramide, cyclizine, and 5HT3 receptor antagonists (such as granisetron) to treat nausea and vomiting. It is particularly useful for Parkinson's patients because it does not cross the blood-brain barrier. Not available in the U.S. Read more...
More about motilium
See the wikipedia entry:http://en.wikipedia.org/wiki/Domperidoneand drugs.com:http://www.drugs.com/cons/motilium-reg.html

Source: PatientsLikeMe

Selegiline

Here is some additional info:"This medication is used to treat movement disorders caused by Parkinson's disease. It does not cure Parkinson's disease, but it may improve shakiness (tremor), muscle stiffness, loss of normal movement as your dose of other Parkinson's medication wears off (end-of-dose failure), and sudden switching between normal movement and stiffness ("on-off" problems). It may improve your range of motion and ability to walk, dress, and exercise. Selegiline is usually used in combination with other medicines (e.g., levodopa, carbidopa).
Selegiline is an enzyme blocker (MAO inhibitor) that works by slowing the breakdown of certain natural substances in the brain (neurotransmitters such as dopamine, norepinephrine, and serotonin).How to use Selegiline
Take this medication by mouth, usually twice daily with breakfast and lunch. Taking selegiline late in the day may cause trouble sleeping. Dosage is based on your medical condition and response to therapy. The usual highest dose is 5 milligrams twice a day. Do not increase your dose or take it more often than directed.
After you have been taking selegiline for 2 or 3 days, your doctor may direct you to lower your levodopa dose. Follow your doctor's instructions closely. Do not stop or change the dose of any of your medications without first talking with your doctor.
It may take a few weeks for the full benefits of the drug to be noticed. Do not stop taking this drug without first consulting your doctor. Talk with your doctor if the medication stops working well or if your condition worsens.
Dizziness, abdominal pain, dry mouth, nausea, stomach upset, trouble sleeping, and headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.
If you are also taking levodopa, you may experience more side effects from the levodopa when taking selegiline. Tell your doctor immediately if any of these side effects occur: nausea, shakiness, muscle stiffness, mental/mood changes such as hallucinations/abnormal dreams. Your doctor may need to change your medication or dose. Do not stop or change the dose of your levodopa without talking with your doctor first.
Remember that your doctor has prescribed this medication because the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor immediately if any of these unlikely but serious side effects occur: fainting, loss of balance, mental/mood changes (e.g., agitation, confusion, depression, hallucinations), worsening muscle stiffness/twitching, changes in sexual ability/interest, increased shaking (tremor), swollen ankles/legs, difficulty urinating, unusual weight gain.
Tell your doctor immediately if any of these rare but very serious side effects occur: easy bleeding/bruising, black/tarry stools, vomit that looks like coffee grounds.
This drug may rarely cause an attack of extremely high blood pressure (hypertensive crisis), which may be fatal. Many drug and food interactions can increase this risk. (See also Drug Interactions section.) Seek immediate medical attention if any of these serious side effects occur: frequent/severe headache, fast/slow/irregular/pounding heartbeat, chest pain, neck stiffness/soreness, severe nausea/vomiting, sweating/clammy skin (sometimes with fever), widened pupils, vision changes (e.g., double/blurred vision)., sudden sensitivity to light (photophobia).
A serious allergic reaction to this drug is unlikely, but seek immediate medical attention if it occurs. Symptoms of a serious allergic reaction include: rash, itching, swelling, dizziness, trouble breathing.
If you notice other effects not listed above, contact your doctor or pharmacist."

Source :PatientsLikeMe

Speech Therapists

Dear Mr Teo You don't need a speech therapist at the moment. You just need to continue with your Parkinson's medications. Dr Chew
Date: Mon, 12 Nov 2007 04:33:46 -0800From: teokimhoe@yahoo.comSubject: pathologistTo: nkchew33@hotmail.com
Dear Dr.Chew,

Would you recommend Pathologist for me to check on my speech? I find my voice is getting soft.

Thank you


Teo Kim Hoe

Prudent diet associated with reduced risk of PD

Posted: Wed Nov 14, 2007 1:27 pm Post subject: News: Prudent diet associated with reduced risk of PDDear Friends, No diet has been proven to prevent PD, nor to slow its progression. The following study shows an association between a Mediterranean-type diet and lowered risk for PD; this is not proof, but it is encouraging, and certainly is a wise choice. Best, Kathrynne ======= Eating More Fruits, Vegetables, Legumes, Whole Grains, Poultry, and Fish May Reduce the Risk of Parkinson's Disease Reference: "Prospective study of dietary pattern and risk of Parkinson disease," Gao X, Chen H, et al, Am J Clin Nutr, 2007; 86(5): 1486-1494. (Address: X Gao, Department of Nutrition, Harvard School of Public Health, 655 Huntington Avenue, Boston, MA 02115, USA. E-mail: xgao@hsph.harvard.edu ). Summary: In a prospective study involving 49,692 men and 81,676 women, results indicate that greater adherence to dietary patterns characterized by a high intake of fruit, vegetables, fish, poultry, legumes, whole grains, and nuts, a low intake of saturated fat, and a moderate intake of alcohol may reduce the risk of Parkinson's Disease (PD). Using principal components analysis, two dietary patterns were identified: 1) prudent dietary pattern, characterized by high intakes of fruit, vegetables, legumes, whole grains, and fish; 2) Western diet, characterized by higher intakes of red and processed meats, sweets and desserts, french fries, and refined grains. After adjusting for potential confounders, subjects in the highest quintile of adherence to the prudent dietary pattern showed a 22% reduced risk of PD, compared to subjects in the lowest quintile. Similarly, using the Alternate Healthy Eating Index (AHEI), subjects in the highest quintile of AHEI score, suggesting the highest diet quality, showed a 30% reduced risk of PD, compared to subjects in the lowest quintile. Furthermore, using the alternate Mediterranean Diet Score (aMED), the highest quintile of aMED score was associated with a 25% reduced risk of PD, compared with the lowest quintile. Thus, the authors of this study conclude, "Dietary patterns with a high intake of fruit, vegetables, legumes, whole grains, nuts, fish, and poultry and a low intake of saturated fat and a moderate intake of alcohol may protect against PD." http://www.vitasearch.com/CP/weeklyupdates/_____

Fatigue

Fatigue may refer to several things in neurological diseases:1.) A generalized lack of energy. 2.) A reduction in the force of individual muscle contractions; overlaps with weakness and atrophy.3.) A psychological state consistent with apathy, inertia, or lack of motivation such as occurs in depression. 4.) Daytime sleepiness caused by poor sleep quality or medication side effects. The management of fatigue is important because it is associated with poor quality of life. There are several targets for treatment. Firstly, sleep quality must be considered. Poor sleep hygiene, anxiety, inability to turn in bed, pain, or breathing difficulties could cause insomnia, leading to daytime sleepiness, irritability, and poor cognitive function. Treatment of these underlying causes may be beneficial. Secondly, poor respiratory function could lead to lack of oxygen for the brain and muscles. Non-invasive ventilation either at night or for periods of the day may be helpful. Thirdly, mood factors such as anxiety and depression can cause psychological feelings of fatigue or inertia, which may respond to drugs or counseling. Finally, a wakefulness-promoting agent such as Modafinil may be prescribed to combat fatigue.
Source: NPF discussion corner

Cutdpwn medication

Dear Mr Teo

Just take Sinemet one tablet a day and Requip 4 mg three times a day.

Dr Chew

Date: Sat, 19 Jan 2008 02:05:43 -0800From: teokimhoe@yahoo.comSubject: Re: cutdown medicationTo: nkchew33@hotmail.com
Dear Dr. Chew,


I lost my power (endurance) when I do boxing exercises after 15 minutes and could not continue. However I am glad to inform you that my balance is improving as I could kick and push my trainer with my single leg off and on for 15 minutes each time.

I am sorry to inform you that I cutdown my medication without informing you i.e Sinement 25/100 gm one dosage in the morning only with 12 gm of requip daily.

Should I continue the medication to stay with 3 dosages of 25/100 Sinemet and 12 dosages of requip daily as your instruction? Kindly advise.

Best regards

Yours faithfully,

Teo Kim HOe

You're not sick, you're thirsty by F.Batmanghelidj

Teo, I don't know if you read all of the posts / replies so I am copying part of a reply that I sent to a post about Dehydration and PD. I would like your opinion as to what your thoughts are about the quoted material. Thanks, Janice (auntique) The book , "YOU'RE NOT SICK, YOU'RE THIRSTY" 'Water for Health, for Healing, for Life' by F. Batmanghelidj (Warner Books) will really open your eyes up to some things that we may be taking meds for that drinking more water would 'fix.' To quote a parargraph that I found extremely interesting: (please note I am not suggesting anything by quoting this to you, only sharing what the book says)'DEHYDRATION CAN CAUSE A BREACH IN THE BLOOD-BRAIN BARRIER. ANY SUCH BREACH COMPROMISES THE INTEGRITY OF NORMAL BRAIN FUNCTIONS. I (the author) AM OF THE STRONG OPINION THAT DEHYDRATION THAT COMPROMISES THE PROTECTIVE SHIELD OF THE BLOOD-BRAIN BARRIER IS THE PRIMARY CAUSE OF MOST OF THE DISEASES OF THE CENTRAL NERVOUS SYSTEM. WHEN THE BARRIER BECOMES COMPROMISED, THE SOLID WASTE OF SUCH MICROSCOPIC BLEEDINGS IS CONVERTED INTO PLAQUES THAT ARE THE HALLMARKS OF MOST NEUROLOGICAL DISORDERS, SUCH AS MULTIPLE SCLEROSIS, PARKINSON'S DISEASE, AND ALZHEIMER'S DISEASE. I (the author) THINK THE SAME PROCESS TAKES PLACE IN MIGRAINE HEADACHES.'

Dear Mr Teo

Water is the one of the most important components of cells in many vital organs (including the brain). Water plays a major role in maintaining the integrity of the blood-brain barrier. Thus, dehydration certainly causes brain cell dysfunction. However, it difficult to ascertain whether the degree of cell dysfunction, due to dehydration, is sufficient to lead to brain diseases such as Parkinson's Disease. Dr Chew

Source: PatientslikeMe