Posted: Sat Jul 14, 2007 5:24 am Post subject: Saliva and PDPosted:周六2007年7月14日5:24分邮政主题:唾液和PD
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Dear Doctor,亲爱的医生,
As there are 70-80% PD patients have saliva drooling from the mouth.由于有70-80%的帕金森病患者有流涎唾液从嘴里. I am one of them.我也是其中之一.
Kindly elaborate the cause of the saliva drooling from the mouth?请说明原因的唾沫口水从口?
What kind of treatment to stop it from drooling?什么样的治疗,以阻止它垂涎?
As For me I have the saliva drooling after I have taken the requip 2mg three times a day.至于我,我的口水唾液后,我所采取的requip2mg/只每天三次.
Best regards问候
Teo Kim Hoe张志贤金锄头
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Dr. Fernandez费尔南德斯博士
Joined: 20 Jan 2007加入:2007年1月20日
Posts: 90职位:90
Posted: Sat Jul 14, 2007 8:03 am Post subject:Posted:周六2007年7月14日9:01分邮政主题:
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Drooling (or sialorrhea) is common in PD.流涎(口水)是常见的肢体. For the most part the cause is not increased saliva production but slowed reflex in automatically swallowing the natural saliva that accumulated in the mouth throughout the day.对大部份的原因是没有增加唾液生产减缓,但反射自动吞咽的唾液自然这样积累的嘴整整一天.
You see, a person without PD does not even notice that saliva is constantly being produced (it is done so to lubricate the whole mouth for talking, eating, etc).你看!一个人没有肢体甚至不公告,唾液不断产生的影响(这是做注油整个嘴来说话,吃东西等). This is because after a certain volume is accumulated, this is automatically swallowed without even thinking about it.这是因为经过一定量的积累,这是自动吞下连思考. But in PD, this automatic swallowing is sometimes lost, thus the salive pools and drools on the side of the mouth.但在PD,这种自动吞咽有时会丢失,因此唾液池及嘴角站在一边的嘴.
The best analogy I can give you is when you go to the dentist and you are told to keep you mouth wide open.最好的比喻,我可以给你的是,当你到牙医,你告诉他们保持你的口是敞开的. You will notice that after some time, your saliva pools and the dentist either has a suction device or allows you to spit/gargle.你会发现,经过一段时间,你的唾液池及牙医要么有吸尘装置,或者允许你呸/含漱. You did not really have increased salivary production at the dentist's office, but you were not allowed to swallow, thus the pooling of saliva.你没有真正增加唾液生产牙医办公室,但你不能吞食,因此,汇聚了唾沫.
The simplest strategy for this is to simply suck sugar-free (to prevent cavities) candy or chew sugar-free gum all day.最简单的策略,因为这是简单地吸吮无糖(防止蛀牙)糖果,或嚼无糖口香糖一整天. This will trigger your mouth to swallow.这将引发你的嘴吞下.
Sometimes, anticholinergic drugs are used to decrease salivary production (they cause dry mouth).有时,抗胆碱药物,是用来减少唾液生产(它们造成口干). But that is not really addressing the problem since the issue is not increased salivary production.但那不是真正解决了问题,因为问题的关键不是增加唾液生产. It also has lots of side effects (cognitive slowing, blurred vision, urinary hesitancy, etc).它也有很多副作用(认知缓慢,视力模糊,尿液犹豫不决等).
The best therapy, in my opinion, is botulinum toxin injection of the parotid and submandibular gland.最好的治疗,我认为这是肉毒杆菌毒素注射的腮腺和颌下腺. We have some reason to believe that Botox Type B is better than Type A for this indication.我们有理由相信,肉毒杆菌毒素B型比A型这种迹象. But either is generally okay.但无论是一般感冒.
Yours,万事如意
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Hubert H. Fernandez朱佩h.费尔南德斯
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Anonymous匿名
Posted: Sat Jul 14, 2007 9:40 am Post subject:Posted:周六2007年7月14日上午09点40分邮政主题:
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Dear Doctor,亲爱的医生,
I refer to the above I have the following for your advise:我指的是段,我有以下几点建议您:
1 Is it the drooling or sialorrhea resulted by the jaw tremor?1,是它的口水还是口水造成的下颚颤抖?
2.2. Is it the neurological disorders associated with drooling of saliva?它是神经病变与口水唾液?
3.Is it an impact on lip, tongue, and jaw in PD speaker intellectuality and articulately?3.is它影响到嘴唇,舌头,下巴钯议长理智与加伊达?
4.4. Is it reduced spontaneous swallowing?它是减少腹水吞下?
5 Are the above contribute to a poor quality of life and a career burden.?5以上的贡献,为穷人的生活质量和事业的负担.?
Best regards问候
TEOKIMHOEteokimhoe
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Dr. Fernandez费尔南德斯博士
Joined: 20 Jan 2007加入:2007年1月20日
Posts: 90职位:90
Posted: Sat Jul 14, 2007 10:51 pm Post subject:Posted:周六2007年7月14日10:51分邮政主题:
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Drooling is not a result of jaw tremor.流口水是不是因下颚颤抖.
If often has no/minimal impact on lip, tongue, jaw or speaking/articulation.如果常常没有/影响微乎其微,嘴唇,舌头,下巴或演讲/articulation.
It is, as I mentioned, often a result of slowed or impaired natural/normal reflex to swallow the saliva regularly.但正如我所说,往往因放慢或受损自然/正常反射吞下唾液定期举行.
Yes, if drooling is severe, it can affect quality of life.不错,如果流口水是非常严重的,它可以影响生活质量.
Yours,万事如意
__________________________________
Hubert H. Fernandez朱佩h.费尔南德斯
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Anonymous匿名
Posted: Sun Jul 15, 2007 12:24 am Post subject:张贴:孙2007年7月15日12:24分邮政主题:
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Dear Doctor,亲爱的医生,
I have a hypothesis about the saliva.我有一个假说,唾液. I sometimes suddenly feel a lot of saliva pooling in the front of my mouth.有时,我突然感到了不少口水汇集在门口把我的嘴. But it但
is only sometimes.只是有时候. True, I may not be swallowing it as well as once but I am *sure* it feels like a sudden surge of saliva being produced and as I have had parotid gland issues before I think I know what that feels like.不错,我未必是它吞下以及一次,但我相信**感觉突然唾液出炉,而正如我曾腮腺问题之前,我想我知道是什么感觉喜欢.
I was diagnosed with Sjogren's Syndrome years ago.我被诊断患有干燥综合征多年前. There was at times a very dry mouth and other times too much saliva as the parotid tried to make up for the deficit.有次在一个非常口干,其他时间太多,因为唾液腮腺试图使弥补赤字. Dry eyes also watering (as a reaction to the dryness), etc. You probably know this disease.眼睛干涩也是浇水(作为一种反应干燥)等,你大概知道这种病.
My point is that if one has this disease (Sjogren's) they don't recover the cells destroyed and theoretically the damage is done.我的意思是,如果你有这病(干燥),他们不收回摧毁细胞,从理论上损害做到这一点. However, after a time all these secretions went back into balance for me.不过,经过一段时间,这些分泌物回去权衡了. I was then told that it was not "true" Sjogren's but that my symptoms were a result of a disturbed autonomic nervous system, specifically sympathetic, as a part of my Fibromyalgia.当时我说那不是"真实"格伦说,但我的症状都造成了困扰植物神经系统,特别同情,并以此作为我国纤维肌痛.
I did a little research and lo, and behold, it seems very possible that this is true -- the sympathetic nervous system a little out of whack could cause too much saliva production in the same way it can cause some of the other commonly mentioned sympathetic nervous system issues.我作了一个小小的研究,螺,看吧,看来,极有可能这是一个事实--交感神经系统有点格格不入失衡可能导致太多的唾液生产一样,它可以导致其他一些常提到的交感神经系统问题.
My point is that I have read that sympathetic nervous system dysfunction is commonly found in PD.我的意思是,我已看过,交感神经系统功能障碍是常见的并发症. I hypothesize a connection to the excess saliva.我猜测联想的唾液过多. Every single book or article one reads says the same thing -- poor swallowing --I think mostly because it's not that important to researchers and one copies the others' remarks.每一本书或文章,一款是说,同样的事情--穷人吞咽--我想主要是因为它的不这一重要的研究者之一,拷贝他人的言论. But I am guessing if you asked a lot of patients they might say they feel surges of saliva (like when you are hungry and smell a hamburger!).但我猜测,如果你问了很多病人,他们可能会说,他们感到袭来的唾液(如当你饿了,闻到一个汉堡包!!).
Since you doctors are always very sympathetic to the quality of life issues the excess saliva and drooling can cause I thought I would mention it.因为你的医生总是非常同情的生活质量问题过多唾液和口水可造成我以为我会提到它. Also, it could explain good results from the bot ox rather than a bone dry miserable mouth because the botox would be inhibiting the *excess* saliva.另外,它可以解释好成绩,从肉毒而非骨干口苦,因为肉毒会抑制过剩**唾液.
Well, not that you asked my views .好,而不是你问我的意见. .. .but there you have it!.但你有!
Best wishes.良好的祝愿.
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Dr. Fernandez费尔南德斯博士
Joined: 20 Jan 2007加入:2007年1月20日
Posts: 90职位:90
Posted: Sun Jul 15, 2007 7:57 am Post subject:张贴:孙2007年7月15日上午07点57分邮政主题:
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Your views are always welcome.你的意见都是欢迎的.
But we do care about drooling and research is being done on the field.但我们关心的口水和研究,正在做有关的领域.
We now offer botox for this, which was not offered even 5 years ago!我们现在所提供的肉毒毒素,这也是无法提供,甚至5年前!
Yours,万事如意
__________________________________
Hubert H. Fernandez朱佩h.费尔南德斯
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Anonymous匿名
Posted: Mon Jul 16, 2007 5:40 am Post subject: Saliva and PDPosted:周一2007年7月16日上午05点40分邮政主题:唾液和PD
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Dear Doctor,''亲爱的医生,''
I am given to take Benzhexol HCL 2mg for my drooling of saliva i.e. 1 tablet 3 times a day.能给我以盐酸苯2mg/只对我的口水唾液,即1片,每日3次.
i am told that BTX is expensive and has to be given every three months as it is effective for three months only.告诉我的BTX非常昂贵,而且也可以获得每三个月,因为它是有效的只用三个月.
As for antidepression I am given to take 2 tablets of Seroquel 25mg and 1/2 tablet of Rivotril 0,5mg at night.至于抗抑郁能给我以2粒思瑞康93.4%,93.3%和1/2片rivotril0,5毫克时夜. I stop taking Zyprexa Zydis as it worsen the PD patient.我停止服用用药zydis因为关爱帕金森病人.
Kindly advise善意提醒
TEOKIMHOE
Posted: Mon Jul 16, 2007 3:17 pm Post subject:Posted:周一2007年7月16日下午03点17分邮政主题:
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Dr. F --六博士--
I hope you read my remark acknowledging that you DO care.我希望你看过我的话承认你的照顾. I wasn't sure from what you said.我不知道你刚才说的. You guys (people) are so你的男孩(人)等
compassionate.富于同情心. It's just heartening to know you are out there.这只是欣慰地知道你在那里.
Best wishes.良好的祝愿.
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Dr. Rodriguez罗德里格斯博士
Joined: 22 Jan 2007加入:2007年1月22日
Posts: 92职位:92
Location: Gainesville, Fl位置:斯维尔,外语
Posted: Mon Jul 16, 2007 4:20 pm Post subject:Posted:周一2007年7月16日4:20分邮政主题:
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Teo:张志贤:
The Benzhexol is fine, but be aware that it may cause confusion or mental slowness in some patients.苯的是好的,但要知道这可能会引起混淆或智力迟钝在一些病人. If it is not causing any problem to you, you can stay on it.如果是不会造成任何问题,你便可以留在这.
This is why Botulinum toxin is an option, because avoids this type of side effects, quite common in some PD patients.这就是为什么肉毒杆菌毒素是一种选择,因为可避免这种副作用相当普遍,在一些PD患者.
As for your depression, I prefer medications like SSRi's (serotonin reuptake inhibitors) like Lexapro or Zoloft before trying the Seroquel.至于你的抑郁症,我宁愿服用类及SSRI(血清素再吸收抑制剂)lexapro象或舍曲之前尝试的思瑞康. I am fine with the Rivotril.我的罚款与rivotril. The Seroquel is especially helpful in depressed patient with some psychotic symptoms.思瑞康的,尤其是帮助抑郁症患者有精神病症状.
Hope this helps.希望这有助于.
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Ramon L Rodriguez, MDL号拉蒙罗德里格斯,海事
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